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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKNK2
All Species:
39.09
Human Site:
S270
Identified Species:
78.18
UniProt:
Q9HBH9
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HBH9
NP_060042.2
465
51875
S270
E
A
F
S
E
E
A
S
I
Y
D
K
R
C
D
Chimpanzee
Pan troglodytes
XP_512248
805
84821
S597
E
A
F
S
E
E
A
S
I
Y
D
K
R
C
D
Rhesus Macaque
Macaca mulatta
XP_001117579
489
54064
S294
E
A
F
S
E
E
A
S
I
Y
D
K
R
C
D
Dog
Lupus familis
XP_855041
1044
109683
S862
E
A
F
S
E
E
A
S
I
Y
D
K
R
C
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDB0
459
51614
S270
E
A
F
S
E
E
A
S
I
Y
D
K
R
C
D
Rat
Rattus norvegicus
Q5U2N4
459
51555
S270
E
A
F
S
E
E
A
S
I
Y
D
K
R
C
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235171
508
56331
T318
E
V
F
T
E
E
A
T
F
Y
D
K
R
C
D
Frog
Xenopus laevis
Q6P431
467
52653
S269
E
A
F
N
E
E
A
S
I
Y
D
K
R
C
D
Zebra Danio
Brachydanio rerio
NP_997888
472
52923
S270
E
A
F
N
E
E
A
S
I
Y
D
K
R
C
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731624
1090
123424
H253
D
L
F
V
G
E
A
H
Y
Y
D
K
R
C
D
Honey Bee
Apis mellifera
XP_395927
516
58135
N243
E
A
F
I
G
E
A
N
Y
Y
D
K
R
C
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779905
511
56921
T304
F
I
Y
D
L
Q
A
T
V
Y
D
K
R
C
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.8
92.4
34.6
N.A.
92.6
92.6
N.A.
N.A.
60.8
76.8
73.3
N.A.
24
49.8
N.A.
48.7
Protein Similarity:
100
48.5
93.4
36.8
N.A.
95.2
95.2
N.A.
N.A.
73
87.7
84.5
N.A.
31
66.6
N.A.
64.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
73.3
93.3
93.3
N.A.
60
73.3
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
100
100
N.A.
66.6
80
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
75
0
0
0
0
100
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% C
% Asp:
9
0
0
9
0
0
0
0
0
0
100
0
0
0
100
% D
% Glu:
84
0
0
0
75
92
0
0
0
0
0
0
0
0
0
% E
% Phe:
9
0
92
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
9
0
0
0
0
67
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% K
% Leu:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
17
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% R
% Ser:
0
0
0
50
0
0
0
67
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
9
0
0
0
17
0
0
0
0
0
0
0
% T
% Val:
0
9
0
9
0
0
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
17
100
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _